Antiviral drug resistance in Cuban children infected with HIV-1
نویسندگان
چکیده
منابع مشابه
HIV drug resistance in HIV-infected children.
Almeida et al. report, in this issue of the journal, a retrospective studyon theprevalence and patterns of antiretroviral drug resistance in 24 treatment-naïve and 23 treatment-experienced children failing therapy between 2000 and 2004 attending a clinic in São Paulo. All children were vertically infected, and the median age of the naïveand treatment-experienced children was 22 months and 102 m...
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Our goal was to describe the presence of HIV drug resistance among HIV-1-infected, antiretroviral (ARV) naïve children and adolescents in Latin America and to examine resistance in these children in relation to drug exposure in the mother. Genotyping was performed on plasma samples obtained at baseline from HIV-1-infected participants in a prospective cohort study in Brazil, Argentina, and Mexi...
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Results Among those who had been on ART for a median period of 24 months 51 children (83.6%) achieved virological suppression. There were 10 children with virological failure, and only two amongst these manifested immunological failure. Nine children (90%) had reverse transcriptase-related DRMs, and none had protease inhibitor-related DRMs. The most frequent NRTI mutation was M184V (n=9) follow...
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TheWorld Health Organization (WHO) estimates that two million children younger than 15 years are infected with HIV-1. Although most HIV-1-infected children are in Sub-Saharan Africa, more than 10,000 of theestimated730,000HIV-1-infectedpersons in Brazil are likely to be children. The extent of the HIV-1 epidemic in children reflects the risk factors for HIV-1 infection in the adult population a...
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In pediatric and adult patients after stem cell transplantation (SCT) disseminated infections caused by human cytomegalovirus (HCMV) can cause life threatening diseases. For treatment, the three antivirals ganciclovir (GCV), foscarnet (PFA) and cidofovir (CDV) are approved and most frequently used. Resistance to all of these antiviral drugs may induce a severe problem in this patient cohort. Re...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2012
ISSN: 1758-2652
DOI: 10.7448/ias.15.6.18186